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ECO403 PAST PAPERS

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Some chemical substances can connect to and modify nucleotide websites. For
For instance, nitrous acid (HNO2) and its family members might return
Degradation of cytosines in DNA happens within the urease: they convert an amino group to a cytosine (-NH2) keto.
group (-c = o). This modification has an identical consequence
Spontaneous emission:

DNA polymerase A (fundamental pairs with U as an alternative of G)
Some chemical substances add the group to the inspiration. For instance, penicillin, a element of cigarette smoke, is considerably elevated.

Chemical group in Guanine, which isn’t obtainable
fundamental coupling. When DNA polymerase reaches like this
Modified guanine, which joins any of the 4 bases; ng
In fact, three-quarters of the inserted web site
Cytosine and mutation shouldn’t consequence.

Radiation damages genetic materials in two methods. ionized
Radiation (X-rays) produce extremely reactive chemical substances known as free radicals that change websites
unknown DNA sample (by DNA polymerase) or
Sugar – breaks the phosphate spine, which causes chromosomal abnormalities.

UV radiation from the solar (or
tanning lamp) is absorbed into the DNA by thymine
It varieties parallel covalent bonds with adjoining nucleotides. It additionally destroys the DNA copy.

 

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